Resveratrol Protects DAergic PC12 Cells from High Glucose-Induced Oxidative Stress and Apoptosis: Effect on p53 and GRP75 Localization
Identifieur interne : 000C81 ( Main/Exploration ); précédent : 000C80; suivant : 000C82Resveratrol Protects DAergic PC12 Cells from High Glucose-Induced Oxidative Stress and Apoptosis: Effect on p53 and GRP75 Localization
Auteurs : Justine Renaud ; Julie Bournival ; Ximena Zottig ; Maria-Grazia MartinoliSource :
- Neurotoxicity Research [ 1029-8428 ] ; 2013.
Abstract
Resveratrol (RESV), a polyphenolic natural compound, has long been acknowledged to have cardioprotective and antiinflammatory actions. Evidence suggests that RESV has antioxidant properties that reduce the formation of reactive oxygen species leading to oxidative stress and apoptotic death of dopaminergic (DAergic) neurons in Parkinson’s disease (PD). Recent literature has recognized hyperglycemia as a cause of oxidative stress reported to be harmful for the nervous system. In this context, our study aimed (a) to evaluate the effect of RESV against high glucose (HG)-induced oxidative stress in DAergic neurons, (b) to study the antiapoptotic properties of RESV in HG condition, and c) to analyze RESV’s ability to modulate p53 and GRP75, a p53 inactivator found to be under expressed in postmortem PD brains. Our results suggest that RESV protects DAergic neurons against HG-induced oxidative stress by diminishing cellular levels of superoxide anion. Moreover, RESV significantly reduces HG-induced apoptosis in DAergic cells by modulating DNA fragmentation and the expression of several genes implicated in the apoptotic cascade, such as Bax, Bcl-2, cleaved caspase-3, and cleaved PARP-1. RESV also prevents the pro-apoptotic increase of p53 in the nucleus induced by HG. Such data strengthens the correlation between hyperglycemia and neurodegeneration, while providing new insight on the high occurrence of PD in patients with diabetes. This study enlightens potent neuroprotective roles for RESV that should be considered as a nutritional recommendation for preventive and/or complementary therapies in controlling neurodegenerative complications in diabetes.
Url:
DOI: 10.1007/s12640-013-9439-7
PubMed: 24218232
PubMed Central: 3889681
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000268
- to stream Pmc, to step Curation: 000268
- to stream Pmc, to step Checkpoint: 000588
- to stream Ncbi, to step Merge: 001611
- to stream Ncbi, to step Curation: 001611
- to stream Ncbi, to step Checkpoint: 001611
- to stream Main, to step Merge: 000C88
- to stream Main, to step Curation: 000C81
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Resveratrol Protects DAergic PC12 Cells from High Glucose-Induced Oxidative Stress and Apoptosis: Effect on p53 and GRP75 Localization</title><author><name sortKey="Renaud, Justine" sort="Renaud, Justine" uniqKey="Renaud J" first="Justine" last="Renaud">Justine Renaud</name><affiliation><nlm:aff id="Aff1">Cellular Neurobiology, Department of Medical Biology, Université du Québec à Trois-Rivières, Trois-Rivières, QC G9A 5H7 Canada</nlm:aff><wicri:noCountry code="subfield">QC G9A 5H7 Canada</wicri:noCountry></affiliation></author><author><name sortKey="Bournival, Julie" sort="Bournival, Julie" uniqKey="Bournival J" first="Julie" last="Bournival">Julie Bournival</name><affiliation><nlm:aff id="Aff1">Cellular Neurobiology, Department of Medical Biology, Université du Québec à Trois-Rivières, Trois-Rivières, QC G9A 5H7 Canada</nlm:aff><wicri:noCountry code="subfield">QC G9A 5H7 Canada</wicri:noCountry></affiliation></author><author><name sortKey="Zottig, Ximena" sort="Zottig, Ximena" uniqKey="Zottig X" first="Ximena" last="Zottig">Ximena Zottig</name><affiliation><nlm:aff id="Aff1">Cellular Neurobiology, Department of Medical Biology, Université du Québec à Trois-Rivières, Trois-Rivières, QC G9A 5H7 Canada</nlm:aff><wicri:noCountry code="subfield">QC G9A 5H7 Canada</wicri:noCountry></affiliation></author><author><name sortKey="Martinoli, Maria Grazia" sort="Martinoli, Maria Grazia" uniqKey="Martinoli M" first="Maria-Grazia" last="Martinoli">Maria-Grazia Martinoli</name><affiliation><nlm:aff id="Aff1">Cellular Neurobiology, Department of Medical Biology, Université du Québec à Trois-Rivières, Trois-Rivières, QC G9A 5H7 Canada</nlm:aff><wicri:noCountry code="subfield">QC G9A 5H7 Canada</wicri:noCountry></affiliation><affiliation><nlm:aff id="Aff2">Neuroscience Research Unit, Centre de recherche, Université Laval, Ste-Foy, QC G1V 4G2 Canada</nlm:aff><wicri:noCountry code="subfield">QC G1V 4G2 Canada</wicri:noCountry></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">24218232</idno><idno type="pmc">3889681</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889681</idno><idno type="RBID">PMC:3889681</idno><idno type="doi">10.1007/s12640-013-9439-7</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">000268</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000268</idno><idno type="wicri:Area/Pmc/Curation">000268</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000268</idno><idno type="wicri:Area/Pmc/Checkpoint">000588</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000588</idno><idno type="wicri:Area/Ncbi/Merge">001611</idno><idno type="wicri:Area/Ncbi/Curation">001611</idno><idno type="wicri:Area/Ncbi/Checkpoint">001611</idno><idno type="wicri:doubleKey">1029-8428:2013:Renaud J:resveratrol:protects:daergic</idno><idno type="wicri:Area/Main/Merge">000C88</idno><idno type="wicri:Area/Main/Curation">000C81</idno><idno type="wicri:Area/Main/Exploration">000C81</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Resveratrol Protects DAergic PC12 Cells from High Glucose-Induced Oxidative Stress and Apoptosis: Effect on p53 and GRP75 Localization</title><author><name sortKey="Renaud, Justine" sort="Renaud, Justine" uniqKey="Renaud J" first="Justine" last="Renaud">Justine Renaud</name><affiliation><nlm:aff id="Aff1">Cellular Neurobiology, Department of Medical Biology, Université du Québec à Trois-Rivières, Trois-Rivières, QC G9A 5H7 Canada</nlm:aff><wicri:noCountry code="subfield">QC G9A 5H7 Canada</wicri:noCountry></affiliation></author><author><name sortKey="Bournival, Julie" sort="Bournival, Julie" uniqKey="Bournival J" first="Julie" last="Bournival">Julie Bournival</name><affiliation><nlm:aff id="Aff1">Cellular Neurobiology, Department of Medical Biology, Université du Québec à Trois-Rivières, Trois-Rivières, QC G9A 5H7 Canada</nlm:aff><wicri:noCountry code="subfield">QC G9A 5H7 Canada</wicri:noCountry></affiliation></author><author><name sortKey="Zottig, Ximena" sort="Zottig, Ximena" uniqKey="Zottig X" first="Ximena" last="Zottig">Ximena Zottig</name><affiliation><nlm:aff id="Aff1">Cellular Neurobiology, Department of Medical Biology, Université du Québec à Trois-Rivières, Trois-Rivières, QC G9A 5H7 Canada</nlm:aff><wicri:noCountry code="subfield">QC G9A 5H7 Canada</wicri:noCountry></affiliation></author><author><name sortKey="Martinoli, Maria Grazia" sort="Martinoli, Maria Grazia" uniqKey="Martinoli M" first="Maria-Grazia" last="Martinoli">Maria-Grazia Martinoli</name><affiliation><nlm:aff id="Aff1">Cellular Neurobiology, Department of Medical Biology, Université du Québec à Trois-Rivières, Trois-Rivières, QC G9A 5H7 Canada</nlm:aff><wicri:noCountry code="subfield">QC G9A 5H7 Canada</wicri:noCountry></affiliation><affiliation><nlm:aff id="Aff2">Neuroscience Research Unit, Centre de recherche, Université Laval, Ste-Foy, QC G1V 4G2 Canada</nlm:aff><wicri:noCountry code="subfield">QC G1V 4G2 Canada</wicri:noCountry></affiliation></author></analytic><series><title level="j">Neurotoxicity Research</title><idno type="ISSN">1029-8428</idno><idno type="eISSN">1476-3524</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Resveratrol (RESV), a polyphenolic natural compound, has long been acknowledged to have cardioprotective and antiinflammatory actions. Evidence suggests that RESV has antioxidant properties that reduce the formation of reactive oxygen species leading to oxidative stress and apoptotic death of dopaminergic (DAergic) neurons in Parkinson’s disease (PD). Recent literature has recognized hyperglycemia as a cause of oxidative stress reported to be harmful for the nervous system. In this context, our study aimed (a) to evaluate the effect of RESV against high glucose (HG)-induced oxidative stress in DAergic neurons, (b) to study the antiapoptotic properties of RESV in HG condition, and c) to analyze RESV’s ability to modulate p53 and GRP75, a p53 inactivator found to be under expressed in postmortem PD brains. Our results suggest that RESV protects DAergic neurons against HG-induced oxidative stress by diminishing cellular levels of superoxide anion. Moreover, RESV significantly reduces HG-induced apoptosis in DAergic cells by modulating DNA fragmentation and the expression of several genes implicated in the apoptotic cascade, such as Bax, Bcl-2, cleaved caspase-3, and cleaved PARP-1. RESV also prevents the pro-apoptotic increase of p53 in the nucleus induced by HG. Such data strengthens the correlation between hyperglycemia and neurodegeneration, while providing new insight on the high occurrence of PD in patients with diabetes. This study enlightens potent neuroprotective roles for RESV that should be considered as a nutritional recommendation for preventive and/or complementary therapies in controlling neurodegenerative complications in diabetes.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Ahmed, Ss" uniqKey="Ahmed S">SS Ahmed</name></author><author><name sortKey="Santosh, W" uniqKey="Santosh W">W Santosh</name></author><author><name sortKey="Kumar, S" uniqKey="Kumar S">S Kumar</name></author><author><name sortKey="Christlet, Ht" uniqKey="Christlet H">HT Christlet</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Albani, D" uniqKey="Albani D">D Albani</name></author><author><name sortKey="Polito, L" uniqKey="Polito L">L Polito</name></author><author><name sortKey="Signorini, A" uniqKey="Signorini A">A Signorini</name></author><author><name sortKey="Forloni, G" uniqKey="Forloni G">G Forloni</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Allen, Da" uniqKey="Allen D">DA Allen</name></author><author><name sortKey="Yaqoob, Mm" uniqKey="Yaqoob M">MM Yaqoob</name></author><author><name sortKey="Harwood, Sm" uniqKey="Harwood S">SM Harwood</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Aluyen, Jk" uniqKey="Aluyen J">JK Aluyen</name></author><author><name sortKey="Ton, Qn" uniqKey="Ton Q">QN Ton</name></author><author><name sortKey="Tran, T" uniqKey="Tran T">T Tran</name></author><author><name sortKey="Yang, Ae" uniqKey="Yang A">AE Yang</name></author><author><name sortKey="Gottlieb, Hb" uniqKey="Gottlieb H">HB Gottlieb</name></author><author><name sortKey="Bellanger, Ra" uniqKey="Bellanger R">RA Bellanger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Amiot, Mj" uniqKey="Amiot M">MJ Amiot</name></author><author><name sortKey="Romier, B" uniqKey="Romier B">B Romier</name></author><author><name sortKey="Anh Dao, Tm" uniqKey="Anh Dao T">TM Anh Dao</name></author><author><name sortKey="Fanciullino, R" uniqKey="Fanciullino R">R Fanciullino</name></author><author><name sortKey="Ciccolini, J" uniqKey="Ciccolini J">J Ciccolini</name></author><author><name sortKey="Burcelin, R" uniqKey="Burcelin R">R Burcelin</name></author><author><name sortKey="Pechere, L" uniqKey="Pechere L">L Pechere</name></author><author><name sortKey="Emond, C" uniqKey="Emond C">C Emond</name></author><author><name sortKey="Savouret, Jf" uniqKey="Savouret J">JF Savouret</name></author><author><name sortKey="Seree, E" uniqKey="Seree E">E Seree</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Apel, K" uniqKey="Apel K">K Apel</name></author><author><name sortKey="Hirt, H" uniqKey="Hirt H">H Hirt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bhatt, Jk" uniqKey="Bhatt J">JK Bhatt</name></author><author><name sortKey="Thomas, S" uniqKey="Thomas S">S Thomas</name></author><author><name sortKey="Nanjan, Mj" uniqKey="Nanjan M">MJ Nanjan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Blanchet, J" uniqKey="Blanchet J">J Blanchet</name></author><author><name sortKey="Longpre, F" uniqKey="Longpre F">F Longpré</name></author><author><name sortKey="Bureau, G" uniqKey="Bureau G">G Bureau</name></author><author><name sortKey="Morissette, M" uniqKey="Morissette M">M Morissette</name></author><author><name sortKey="Dipaolo, T" uniqKey="Dipaolo T">T DiPaolo</name></author><author><name sortKey="Bronchti, G" uniqKey="Bronchti G">G Bronchti</name></author><author><name sortKey="Martinoli, Mg" uniqKey="Martinoli M">MG Martinoli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bournival, J" uniqKey="Bournival J">J Bournival</name></author><author><name sortKey="Quessy, P" uniqKey="Quessy P">P Quessy</name></author><author><name sortKey="Martinoli, Mg" uniqKey="Martinoli M">MG Martinoli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bournival, J" uniqKey="Bournival J">J Bournival</name></author><author><name sortKey="Francoeur, Ma" uniqKey="Francoeur M">MA Francoeur</name></author><author><name sortKey="Renaud, J" uniqKey="Renaud J">J Renaud</name></author><author><name sortKey="Martinoli, Mg" uniqKey="Martinoli M">MG Martinoli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brownlee, M" uniqKey="Brownlee M">M Brownlee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bruckbauer, A" uniqKey="Bruckbauer A">A Bruckbauer</name></author><author><name sortKey="Zemel, Mb" uniqKey="Zemel M">MB Zemel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Burbulla, Lf" uniqKey="Burbulla L">LF Burbulla</name></author><author><name sortKey="Schelling, C" uniqKey="Schelling C">C Schelling</name></author><author><name sortKey="Kato, H" uniqKey="Kato H">H Kato</name></author><author><name sortKey="Rapaport, D" uniqKey="Rapaport D">D Rapaport</name></author><author><name sortKey="Woitalla, D" uniqKey="Woitalla D">D Woitalla</name></author><author><name sortKey="Schiesling, C" uniqKey="Schiesling C">C Schiesling</name></author><author><name sortKey="Schulte, C" uniqKey="Schulte C">C Schulte</name></author><author><name sortKey="Sharma, M" uniqKey="Sharma M">M Sharma</name></author><author><name sortKey="Illig, T" uniqKey="Illig T">T Illig</name></author><author><name sortKey="Bauer, P" uniqKey="Bauer P">P Bauer</name></author><author><name sortKey="Jung, S" uniqKey="Jung S">S Jung</name></author><author><name sortKey="Nordheim, A" uniqKey="Nordheim A">A Nordheim</name></author><author><name sortKey="Schols, L" uniqKey="Schols L">L Schöls</name></author><author><name sortKey="Riess, O" uniqKey="Riess O">O Riess</name></author><author><name sortKey="Kruger, R" uniqKey="Kruger R">R Krüger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cao, M" uniqKey="Cao M">M Cao</name></author><author><name sortKey="Jian, J" uniqKey="Jian J">J Jian</name></author><author><name sortKey="Du, Y" uniqKey="Du Y">Y Du</name></author><author><name sortKey="Yan, P" uniqKey="Yan P">P Yan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Carange, J" uniqKey="Carange J">J Carange</name></author><author><name sortKey="Longpre, F" uniqKey="Longpre F">F Longpré</name></author><author><name sortKey="Daoust, B" uniqKey="Daoust B">B Daoust</name></author><author><name sortKey="Martinoli, Mg" uniqKey="Martinoli M">MG Martinoli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chaitanya, Gv" uniqKey="Chaitanya G">GV Chaitanya</name></author><author><name sortKey="Steven, Aj" uniqKey="Steven A">AJ Steven</name></author><author><name sortKey="Babu, Pp" uniqKey="Babu P">PP Babu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Circu, Ml" uniqKey="Circu M">ML Circu</name></author><author><name sortKey="Aw, Ty" uniqKey="Aw T">TY Aw</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cory, S" uniqKey="Cory S">S Cory</name></author><author><name sortKey="Adams, Jm" uniqKey="Adams J">JM Adams</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cui, H" uniqKey="Cui H">H Cui</name></author><author><name sortKey="Kong, Y" uniqKey="Kong Y">Y Kong</name></author><author><name sortKey="Zhang, H" uniqKey="Zhang H">H Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Danielson, Sr" uniqKey="Danielson S">SR Danielson</name></author><author><name sortKey="Andersen, Jk" uniqKey="Andersen J">JK Andersen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Delmas, D" uniqKey="Delmas D">D Delmas</name></author><author><name sortKey="Aires, V" uniqKey="Aires V">V Aires</name></author><author><name sortKey="Limagne, E" uniqKey="Limagne E">E Limagne</name></author><author><name sortKey="Dutarte, P" uniqKey="Dutarte P">P Dutarte</name></author><author><name sortKey="Mazue, F" uniqKey="Mazue F">F Mazué</name></author><author><name sortKey="Ghiringhelli, F" uniqKey="Ghiringhelli F">F Ghiringhelli</name></author><author><name sortKey="Latruffe, N" uniqKey="Latruffe N">N Latruffe</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Du, Q" uniqKey="Du Q">Q Du</name></author><author><name sortKey="Hu, B" uniqKey="Hu B">B Hu</name></author><author><name sortKey="An, Hm" uniqKey="An H">HM An</name></author><author><name sortKey="Shen, Kp" uniqKey="Shen K">KP Shen</name></author><author><name sortKey="Xu, L" uniqKey="Xu L">L Xu</name></author><author><name sortKey="Deng, S" uniqKey="Deng S">S Deng</name></author><author><name sortKey="Wei, Mm" uniqKey="Wei M">MM Wei</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fan, Tj" uniqKey="Fan T">TJ Fan</name></author><author><name sortKey="Han, Lh" uniqKey="Han L">LH Han</name></author><author><name sortKey="Cong, Rs" uniqKey="Cong R">RS Cong</name></author><author><name sortKey="Liang, J" uniqKey="Liang J">J Liang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Foti Cuzzola, V" uniqKey="Foti Cuzzola V">V Foti Cuzzola</name></author><author><name sortKey="Ciurleo, R" uniqKey="Ciurleo R">R Ciurleo</name></author><author><name sortKey="Giacoppo, S" uniqKey="Giacoppo S">S Giacoppo</name></author><author><name sortKey="Marino, S" uniqKey="Marino S">S Marino</name></author><author><name sortKey="Bramanti, P" uniqKey="Bramanti P">P Bramanti</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Frankfurt, Os" uniqKey="Frankfurt O">OS Frankfurt</name></author><author><name sortKey="Krishan, A" uniqKey="Krishan A">A Krishan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gagne, B" uniqKey="Gagne B">B Gagné</name></author><author><name sortKey="Gelinas, S" uniqKey="Gelinas S">S Gélinas</name></author><author><name sortKey="Bureau, G" uniqKey="Bureau G">G Bureau</name></author><author><name sortKey="Lagace, B" uniqKey="Lagace B">B Lagacé</name></author><author><name sortKey="Ramassamy, C" uniqKey="Ramassamy C">C Ramassamy</name></author><author><name sortKey="Chiasson, K" uniqKey="Chiasson K">K Chiasson</name></author><author><name sortKey="Valastro, B" uniqKey="Valastro B">B Valastro</name></author><author><name sortKey="Martinoli, Mg" uniqKey="Martinoli M">MG Martinoli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gelinas, S" uniqKey="Gelinas S">S Gélinas</name></author><author><name sortKey="Martinoli, Mg" uniqKey="Martinoli M">MG Martinoli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Giaccari, A" uniqKey="Giaccari A">A Giaccari</name></author><author><name sortKey="Sorice, G" uniqKey="Sorice G">G Sorice</name></author><author><name sortKey="Muscogiuri, G" uniqKey="Muscogiuri G">G Muscogiuri</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Giacco, F" uniqKey="Giacco F">F Giacco</name></author><author><name sortKey="Brownlee, M" uniqKey="Brownlee M">M Brownlee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gloire, G" uniqKey="Gloire G">G Gloire</name></author><author><name sortKey="Legrand Poels, S" uniqKey="Legrand Poels S">S Legrand-Poels</name></author><author><name sortKey="Piette, J" uniqKey="Piette J">J Piette</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guo, Ww" uniqKey="Guo W">WW Guo</name></author><author><name sortKey="Yang, L" uniqKey="Yang L">L Yang</name></author><author><name sortKey="Liu, Xy" uniqKey="Liu X">XY Liu</name></author><author><name sortKey="Liu, W" uniqKey="Liu W">W Liu</name></author><author><name sortKey="Zuo, J" uniqKey="Zuo J">J Zuo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Haan, C" uniqKey="Haan C">C Haan</name></author><author><name sortKey="Behrmann, I" uniqKey="Behrmann I">I Behrmann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hartmann, A" uniqKey="Hartmann A">A Hartmann</name></author><author><name sortKey="Hirsch, Ec" uniqKey="Hirsch E">EC Hirsch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hu, G" uniqKey="Hu G">G Hu</name></author><author><name sortKey="Jousilahti, P" uniqKey="Jousilahti P">P Jousilahti</name></author><author><name sortKey="Bidel, S" uniqKey="Bidel S">S Bidel</name></author><author><name sortKey="Antikainen, R" uniqKey="Antikainen R">R Antikainen</name></author><author><name sortKey="Tuomilehto, J" uniqKey="Tuomilehto J">J Tuomilehto</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hung, Cw" uniqKey="Hung C">CW Hung</name></author><author><name sortKey="Chen, Yc" uniqKey="Chen Y">YC Chen</name></author><author><name sortKey="Hsieh, Wl" uniqKey="Hsieh W">WL Hsieh</name></author><author><name sortKey="Chiou, Sh" uniqKey="Chiou S">SH Chiou</name></author><author><name sortKey="Kao, Cl" uniqKey="Kao C">CL Kao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jagota, P" uniqKey="Jagota P">P Jagota</name></author><author><name sortKey="Bhidayasiri, R" uniqKey="Bhidayasiri R">R Bhidayasiri</name></author><author><name sortKey="Lang, Ae" uniqKey="Lang A">AE Lang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jin, J" uniqKey="Jin J">J Jin</name></author><author><name sortKey="Meredith, Ge" uniqKey="Meredith G">GE Meredith</name></author><author><name sortKey="Chen, L" uniqKey="Chen L">L Chen</name></author><author><name sortKey="Zhou, Y" uniqKey="Zhou Y">Y Zhou</name></author><author><name sortKey="Xu, J" uniqKey="Xu J">J Xu</name></author><author><name sortKey="Shie, Fs" uniqKey="Shie F">FS Shie</name></author><author><name sortKey="Lockhart, P" uniqKey="Lockhart P">P Lockhart</name></author><author><name sortKey="Zhang, J" uniqKey="Zhang J">J Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jin, J" uniqKey="Jin J">J Jin</name></author><author><name sortKey="Hulette, C" uniqKey="Hulette C">C Hulette</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y Wang</name></author><author><name sortKey="Zhang, T" uniqKey="Zhang T">T Zhang</name></author><author><name sortKey="Pan, C" uniqKey="Pan C">C Pan</name></author><author><name sortKey="Wadhwa, R" uniqKey="Wadhwa R">R Wadhwa</name></author><author><name sortKey="Zhang, J" uniqKey="Zhang J">J Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jin, J" uniqKey="Jin J">J Jin</name></author><author><name sortKey="Li, Gj" uniqKey="Li G">GJ Li</name></author><author><name sortKey="Davis, J" uniqKey="Davis J">J Davis</name></author><author><name sortKey="Zhu, D" uniqKey="Zhu D">D Zhu</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y Wang</name></author><author><name sortKey="Pan, C" uniqKey="Pan C">C Pan</name></author><author><name sortKey="Zhang, J" uniqKey="Zhang J">J Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Johnson, Gl" uniqKey="Johnson G">GL Johnson</name></author><author><name sortKey="Nakamura, K" uniqKey="Nakamura K">K Nakamura</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kadota, T" uniqKey="Kadota T">T Kadota</name></author><author><name sortKey="Yamaai, T" uniqKey="Yamaai T">T Yamaai</name></author><author><name sortKey="Saito, Y" uniqKey="Saito Y">Y Saito</name></author><author><name sortKey="Akita, Y" uniqKey="Akita Y">Y Akita</name></author><author><name sortKey="Kawashima, S" uniqKey="Kawashima S">S Kawashima</name></author><author><name sortKey="Moroi, K" uniqKey="Moroi K">K Moroi</name></author><author><name sortKey="Inagaki, N" uniqKey="Inagaki N">N Inagaki</name></author><author><name sortKey="Kadota, K" uniqKey="Kadota K">K Kadota</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kang, Mh" uniqKey="Kang M">MH Kang</name></author><author><name sortKey="Reynolds, Cp" uniqKey="Reynolds C">CP Reynolds</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kaul, Sc" uniqKey="Kaul S">SC Kaul</name></author><author><name sortKey="Reddel, Rr" uniqKey="Reddel R">RR Reddel</name></author><author><name sortKey="Mitsui, Y" uniqKey="Mitsui Y">Y Mitsui</name></author><author><name sortKey="Wadhwa, R" uniqKey="Wadhwa R">R Wadhwa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kaul, Sc" uniqKey="Kaul S">SC Kaul</name></author><author><name sortKey="Aida, S" uniqKey="Aida S">S Aida</name></author><author><name sortKey="Yaguchi, T" uniqKey="Yaguchi T">T Yaguchi</name></author><author><name sortKey="Kaur, K" uniqKey="Kaur K">K Kaur</name></author><author><name sortKey="Wadhwa, R" uniqKey="Wadhwa R">R Wadhwa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, My" uniqKey="Kim M">MY Kim</name></author><author><name sortKey="Lim, Jh" uniqKey="Lim J">JH Lim</name></author><author><name sortKey="Youn, Hh" uniqKey="Youn H">HH Youn</name></author><author><name sortKey="Hong, Ya" uniqKey="Hong Y">YA Hong</name></author><author><name sortKey="Yang, Ks" uniqKey="Yang K">KS Yang</name></author><author><name sortKey="Park, Hs" uniqKey="Park H">HS Park</name></author><author><name sortKey="Chung, S" uniqKey="Chung S">S Chung</name></author><author><name sortKey="Koh, Sh" uniqKey="Koh S">SH Koh</name></author><author><name sortKey="Shin, Sj" uniqKey="Shin S">SJ Shin</name></author><author><name sortKey="Choi, Bs" uniqKey="Choi B">BS Choi</name></author><author><name sortKey="Kim, Hw" uniqKey="Kim H">HW Kim</name></author><author><name sortKey="Kim, Ys" uniqKey="Kim Y">YS Kim</name></author><author><name sortKey="Lee, Jh" uniqKey="Lee J">JH Lee</name></author><author><name sortKey="Chang, Ys" uniqKey="Chang Y">YS Chang</name></author><author><name sortKey="Park, Cw" uniqKey="Park C">CW Park</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Klein, Jp" uniqKey="Klein J">JP Klein</name></author><author><name sortKey="Hains, Bc" uniqKey="Hains B">BC Hains</name></author><author><name sortKey="Craner, Mj" uniqKey="Craner M">MJ Craner</name></author><author><name sortKey="Black, Ja" uniqKey="Black J">JA Black</name></author><author><name sortKey="Waxman, Sg" uniqKey="Waxman S">SG Waxman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lahaie Collins, V" uniqKey="Lahaie Collins V">V Lahaie-Collins</name></author><author><name sortKey="Bournival, J" uniqKey="Bournival J">J Bournival</name></author><author><name sortKey="Plouffe, M" uniqKey="Plouffe M">M Plouffe</name></author><author><name sortKey="Carange, J" uniqKey="Carange J">J Carange</name></author><author><name sortKey="Martinoli, Mg" uniqKey="Martinoli M">MG Martinoli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lee, Ye" uniqKey="Lee Y">YE Lee</name></author><author><name sortKey="Kim, Jw" uniqKey="Kim J">JW Kim</name></author><author><name sortKey="Lee, Em" uniqKey="Lee E">EM Lee</name></author><author><name sortKey="Ahn, Yb" uniqKey="Ahn Y">YB Ahn</name></author><author><name sortKey="Song, Kh" uniqKey="Song K">KH Song</name></author><author><name sortKey="Yoon, Kh" uniqKey="Yoon K">KH Yoon</name></author><author><name sortKey="Kim, Hw" uniqKey="Kim H">HW Kim</name></author><author><name sortKey="Park, Cw" uniqKey="Park C">CW Park</name></author><author><name sortKey="Li, G" uniqKey="Li G">G Li</name></author><author><name sortKey="Liu, Z" uniqKey="Liu Z">Z Liu</name></author><author><name sortKey="Ko, Sh" uniqKey="Ko S">SH Ko</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, Zg" uniqKey="Li Z">ZG Li</name></author><author><name sortKey="Zhang, W" uniqKey="Zhang W">W Zhang</name></author><author><name sortKey="Grunberger, G" uniqKey="Grunberger G">G Grunberger</name></author><author><name sortKey="Sima, Aa" uniqKey="Sima A">AA Sima</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, Hm" uniqKey="Li H">HM Li</name></author><author><name sortKey="Niki, T" uniqKey="Niki T">T Niki</name></author><author><name sortKey="Taira, T" uniqKey="Taira T">T Taira</name></author><author><name sortKey="Iguchi Ariga, Sm" uniqKey="Iguchi Ariga S">SM Iguchi-Ariga</name></author><author><name sortKey="Ariga, H" uniqKey="Ariga H">H Ariga</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, Yh" uniqKey="Li Y">YH Li</name></author><author><name sortKey="Zhuo, Yh" uniqKey="Zhuo Y">YH Zhuo</name></author><author><name sortKey="Lu, L" uniqKey="Lu L">L Lü</name></author><author><name sortKey="Chen, Ly" uniqKey="Chen L">LY Chen</name></author><author><name sortKey="Huang, Xh" uniqKey="Huang X">XH Huang</name></author><author><name sortKey="Zhang, Jl" uniqKey="Zhang J">JL Zhang</name></author><author><name sortKey="Li, Sy" uniqKey="Li S">SY Li</name></author><author><name sortKey="Wang, Xg" uniqKey="Wang X">XG Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, Hy" uniqKey="Li H">HY Li</name></author><author><name sortKey="Yang, L" uniqKey="Yang L">L Yang</name></author><author><name sortKey="Liu, W" uniqKey="Liu W">W Liu</name></author><author><name sortKey="Zuo, J" uniqKey="Zuo J">J Zuo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu, D" uniqKey="Liu D">D Liu</name></author><author><name sortKey="Xu, Y" uniqKey="Xu Y">Y Xu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Macip, S" uniqKey="Macip S">S Macip</name></author><author><name sortKey="Igarashi, M" uniqKey="Igarashi M">M Igarashi</name></author><author><name sortKey="Berggren, P" uniqKey="Berggren P">P Berggren</name></author><author><name sortKey="Yu, J" uniqKey="Yu J">J Yu</name></author><author><name sortKey="Lee, Sw" uniqKey="Lee S">SW Lee</name></author><author><name sortKey="Aaronson, Sa" uniqKey="Aaronson S">SA Aaronson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Milne, Jc" uniqKey="Milne J">JC Milne</name></author><author><name sortKey="Lambert, Pd" uniqKey="Lambert P">PD Lambert</name></author><author><name sortKey="Schenk, S" uniqKey="Schenk S">S Schenk</name></author><author><name sortKey="Carney, Dp" uniqKey="Carney D">DP Carney</name></author><author><name sortKey="Smith, Jj" uniqKey="Smith J">JJ Smith</name></author><author><name sortKey="Gagne, Dj" uniqKey="Gagne D">DJ Gagne</name></author><author><name sortKey="Jin, L" uniqKey="Jin L">L Jin</name></author><author><name sortKey="Boss, O" uniqKey="Boss O">O Boss</name></author><author><name sortKey="Perni, Rb" uniqKey="Perni R">RB Perni</name></author><author><name sortKey="Vu, Cb" uniqKey="Vu C">CB Vu</name></author><author><name sortKey="Bernis, Je" uniqKey="Bernis J">JE Bernis</name></author><author><name sortKey="Xie, R" uniqKey="Xie R">R Xie</name></author><author><name sortKey="Disch, Js" uniqKey="Disch J">JS Disch</name></author><author><name sortKey="Ng, Py" uniqKey="Ng P">PY Ng</name></author><author><name sortKey="Nunes, Jj" uniqKey="Nunes J">JJ Nunes</name></author><author><name sortKey="Lynch, Av" uniqKey="Lynch A">AV Lynch</name></author><author><name sortKey="Yang, H" uniqKey="Yang H">H Yang</name></author><author><name sortKey="Galonek, H" uniqKey="Galonek H">H Galonek</name></author><author><name sortKey="Isrealian, K" uniqKey="Isrealian K">K Isrealian</name></author><author><name sortKey="Choix, W" uniqKey="Choix W">W Choix</name></author><author><name sortKey="Iffland, A" uniqKey="Iffland A">A Iffland</name></author><author><name sortKey="Lavu, S" uniqKey="Lavu S">S Lavu</name></author><author><name sortKey="Medvedik, O" uniqKey="Medvedik O">O Medvedik</name></author><author><name sortKey="Sinclair, Da" uniqKey="Sinclair D">DA Sinclair</name></author><author><name sortKey="Olefsky, Jm" uniqKey="Olefsky J">JM Olefsky</name></author><author><name sortKey="Jirousek, Mr" uniqKey="Jirousek M">MR Jirousek</name></author><author><name sortKey="Elliott, Pj" uniqKey="Elliott P">PJ Elliott</name></author><author><name sortKey="Westphal, Ch" uniqKey="Westphal C">CH Westphal</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Morris, Kc" uniqKey="Morris K">KC Morris</name></author><author><name sortKey="Lin, Hw" uniqKey="Lin H">HW Lin</name></author><author><name sortKey="Thompson, Jw" uniqKey="Thompson J">JW Thompson</name></author><author><name sortKey="Perez Pinzon, Ma" uniqKey="Perez Pinzon M">MA Perez-Pinzon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nair, Vd" uniqKey="Nair V">VD Nair</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Neilson, Pm" uniqKey="Neilson P">PM Neilson</name></author><author><name sortKey="Cheney, Km" uniqKey="Cheney K">KM Cheney</name></author><author><name sortKey="Li, Cw" uniqKey="Li C">CW Li</name></author><author><name sortKey="Chen, Jd" uniqKey="Chen J">JD Chen</name></author><author><name sortKey="Cawrse, Je" uniqKey="Cawrse J">JE Cawrse</name></author><author><name sortKey="Schulz, Rb" uniqKey="Schulz R">RB Schulz</name></author><author><name sortKey="Powell, Ja" uniqKey="Powell J">JA Powell</name></author><author><name sortKey="Kumar, R" uniqKey="Kumar R">R Kumar</name></author><author><name sortKey="Callen, Df" uniqKey="Callen D">DF Callen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nelson, Le" uniqKey="Nelson L">LE Nelson</name></author><author><name sortKey="Valentine, Rj" uniqKey="Valentine R">RJ Valentine</name></author><author><name sortKey="Cacicedo, Jm" uniqKey="Cacicedo J">JM Cacicedo</name></author><author><name sortKey="Gauthier, Ms" uniqKey="Gauthier M">MS Gauthier</name></author><author><name sortKey="Ido, Y" uniqKey="Ido Y">Y Ido</name></author><author><name sortKey="Ruderman, Nb" uniqKey="Ruderman N">NB Ruderman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Neves, Ar" uniqKey="Neves A">AR Neves</name></author><author><name sortKey="Lucio, M" uniqKey="Lucio M">M Lúcio</name></author><author><name sortKey="Martins, S" uniqKey="Martins S">S Martins</name></author><author><name sortKey="Lima, Jl" uniqKey="Lima J">JL Lima</name></author><author><name sortKey="Reis, S" uniqKey="Reis S">S Reis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pearce, Rk" uniqKey="Pearce R">RK Pearce</name></author><author><name sortKey="Owen, A" uniqKey="Owen A">A Owen</name></author><author><name sortKey="Daniel, S" uniqKey="Daniel S">S Daniel</name></author><author><name sortKey="Jenner, P" uniqKey="Jenner P">P Jenner</name></author><author><name sortKey="Marsden, Cd" uniqKey="Marsden C">CD Marsden</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Perez De La Cruz, V" uniqKey="Perez De La Cruz V">V Pérez-De La Cruz</name></author><author><name sortKey="Elinios Calder N, D" uniqKey="Elinios Calder N D">D Elinios-Calderón</name></author><author><name sortKey="Carrillo Mora, P" uniqKey="Carrillo Mora P">P Carrillo-Mora</name></author><author><name sortKey="Silva Adava, D" uniqKey="Silva Adava D">D Silva-Adava</name></author><author><name sortKey="Konigsberg, M" uniqKey="Konigsberg M">M Konigsberg</name></author><author><name sortKey="Moran, J" uniqKey="Moran J">J Morán</name></author><author><name sortKey="Ali, Sf" uniqKey="Ali S">SF Ali</name></author><author><name sortKey="Chanez Cardenas, Me" uniqKey="Chanez Cardenas M">ME Chánez-Cárdenas</name></author><author><name sortKey="Perez De La Cruz, G" uniqKey="Perez De La Cruz G">G Pérez-De La Cruz</name></author><author><name sortKey="Santamaria, A" uniqKey="Santamaria A">A Santamariá</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Peritore, Cs" uniqKey="Peritore C">CS Peritore</name></author><author><name sortKey="Ho, A" uniqKey="Ho A">A Ho</name></author><author><name sortKey="Yamamoto, Bk" uniqKey="Yamamoto B">BK Yamamoto</name></author><author><name sortKey="Schaus, Se" uniqKey="Schaus S">SE Schaus</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rajabally, Ya" uniqKey="Rajabally Y">YA Rajabally</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rakovic, A" uniqKey="Rakovic A">A Rakovic</name></author><author><name sortKey="Grunewald, A" uniqKey="Grunewald A">A Grünewald</name></author><author><name sortKey="Voges, L" uniqKey="Voges L">L Voges</name></author><author><name sortKey="Hofmann, S" uniqKey="Hofmann S">S Hofmann</name></author><author><name sortKey="Orolicki, S" uniqKey="Orolicki S">S Orolicki</name></author><author><name sortKey="Lohmann, K" uniqKey="Lohmann K">K Lohmann</name></author><author><name sortKey="Klein, C" uniqKey="Klein C">C Klein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rosa, Ft" uniqKey="Rosa F">FT Rosa</name></author><author><name sortKey="Zulet, Ma" uniqKey="Zulet M">MA Zulet</name></author><author><name sortKey="Marchini, Js" uniqKey="Marchini J">JS Marchini</name></author><author><name sortKey="Martinez, Ja" uniqKey="Martinez J">JA Martínez</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rosenow, A" uniqKey="Rosenow A">A Rosenow</name></author><author><name sortKey="Noben, Jp" uniqKey="Noben J">JP Noben</name></author><author><name sortKey="Jocken, J" uniqKey="Jocken J">J Jocken</name></author><author><name sortKey="Kallendrusch, S" uniqKey="Kallendrusch S">S Kallendrusch</name></author><author><name sortKey="Fischer Posovszky, P" uniqKey="Fischer Posovszky P">P Fischer-Posovszky</name></author><author><name sortKey="Mariman, Ec" uniqKey="Mariman E">EC Mariman</name></author><author><name sortKey="Renes, J" uniqKey="Renes J">J Renes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shaikh, S" uniqKey="Shaikh S">S Shaikh</name></author><author><name sortKey="Nicholson, Lf" uniqKey="Nicholson L">LF Nicholson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shi, M" uniqKey="Shi M">M Shi</name></author><author><name sortKey="Jin, J" uniqKey="Jin J">J Jin</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y Wang</name></author><author><name sortKey="Beyer, Rp" uniqKey="Beyer R">RP Beyer</name></author><author><name sortKey="Kitsou, E" uniqKey="Kitsou E">E Kitsou</name></author><author><name sortKey="Albin, Rl" uniqKey="Albin R">RL Albin</name></author><author><name sortKey="Gearing, M" uniqKey="Gearing M">M Gearing</name></author><author><name sortKey="Pan, C" uniqKey="Pan C">C Pan</name></author><author><name sortKey="Zhang, J" uniqKey="Zhang J">J Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Simao, F" uniqKey="Simao F">F Simão</name></author><author><name sortKey="Matte, A" uniqKey="Matte A">A Matté</name></author><author><name sortKey="Pagnussat, As" uniqKey="Pagnussat A">AS Pagnussat</name></author><author><name sortKey="Netto, Ca" uniqKey="Netto C">CA Netto</name></author><author><name sortKey="Salbego, Cg" uniqKey="Salbego C">CG Salbego</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Smith, Dj" uniqKey="Smith D">DJ Smith</name></author><author><name sortKey="Ng, H" uniqKey="Ng H">H Ng</name></author><author><name sortKey="Kluck, Rm" uniqKey="Kluck R">RM Kluck</name></author><author><name sortKey="Nagley, P" uniqKey="Nagley P">P Nagley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Soufi, Fg" uniqKey="Soufi F">FG Soufi</name></author><author><name sortKey="Mohammed Nejad, D" uniqKey="Mohammed Nejad D">D Mohammed-Nejad</name></author><author><name sortKey="Ahmedieh, H" uniqKey="Ahmedieh H">H Ahmedieh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Styskal, J" uniqKey="Styskal J">J Styskal</name></author><author><name sortKey="Van Remmen, H" uniqKey="Van Remmen H">H Van Remmen</name></author><author><name sortKey="Richardson, A" uniqKey="Richardson A">A Richardson</name></author><author><name sortKey="Salmon, Ab" uniqKey="Salmon A">AB Salmon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sun, Y" uniqKey="Sun Y">Y Sun</name></author><author><name sortKey="Chang, Yh" uniqKey="Chang Y">YH Chang</name></author><author><name sortKey="Chen, Hf" uniqKey="Chen H">HF Chen</name></author><author><name sortKey="Su, Yh" uniqKey="Su Y">YH Su</name></author><author><name sortKey="Su, Hf" uniqKey="Su H">HF Su</name></author><author><name sortKey="Li, Cy" uniqKey="Li C">CY Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Szkudelski, T" uniqKey="Szkudelski T">T Szkudelski</name></author><author><name sortKey="Szkudelska, K" uniqKey="Szkudelska K">K Szkudelska</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tatton, Na" uniqKey="Tatton N">NA Tatton</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Tomlinson, Dr" uniqKey="Tomlinson D">DR Tomlinson</name></author><author><name sortKey="Gardiner, Nj" uniqKey="Gardiner N">NJ Gardiner</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Vila, M" uniqKey="Vila M">M Vila</name></author><author><name sortKey="Perier, C" uniqKey="Perier C">C Perier</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Wang, Z" uniqKey="Wang Z">Z Wang</name></author><author><name sortKey="Wang, F" uniqKey="Wang F">F Wang</name></author><author><name sortKey="Tang, T" uniqKey="Tang T">T Tang</name></author><author><name sortKey="Guo, C" uniqKey="Guo C">C Guo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, Pf" uniqKey="Wu P">PF Wu</name></author><author><name sortKey="Xie, N" uniqKey="Xie N">N Xie</name></author><author><name sortKey="Zhang, J" uniqKey="Zhang J">J–J Zhang</name></author><author><name sortKey="Guan, X L" uniqKey="Guan X">X-L Guan</name></author><author><name sortKey="Zhou, J" uniqKey="Zhou J">J Zhou</name></author><author><name sortKey="Li, Longl H" uniqKey="Li L">LongL-H Li</name></author><author><name sortKey="Y L, Xiongq J" uniqKey="Y L X">XiongQ-J Y-L</name></author><author><name sortKey="Zeng, J H" uniqKey="Zeng J">J-H Zeng</name></author><author><name sortKey="Fang Wang, F" uniqKey="Fang Wang F">F Fang Wang</name></author><author><name sortKey="Chen, J G" uniqKey="Chen J">J-G Chen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yaguchi, T" uniqKey="Yaguchi T">T Yaguchi</name></author><author><name sortKey="Aida, S" uniqKey="Aida S">S Aida</name></author><author><name sortKey="Kaul, Sc" uniqKey="Kaul S">SC Kaul</name></author><author><name sortKey="Wadhwa, R" uniqKey="Wadhwa R">R Wadhwa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhou, C" uniqKey="Zhou C">C Zhou</name></author><author><name sortKey="Huang, Y" uniqKey="Huang Y">Y Huang</name></author><author><name sortKey="Przedborski, S" uniqKey="Przedborski S">S Przedborski</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list></list><tree><noCountry><name sortKey="Bournival, Julie" sort="Bournival, Julie" uniqKey="Bournival J" first="Julie" last="Bournival">Julie Bournival</name><name sortKey="Martinoli, Maria Grazia" sort="Martinoli, Maria Grazia" uniqKey="Martinoli M" first="Maria-Grazia" last="Martinoli">Maria-Grazia Martinoli</name><name sortKey="Renaud, Justine" sort="Renaud, Justine" uniqKey="Renaud J" first="Justine" last="Renaud">Justine Renaud</name><name sortKey="Zottig, Ximena" sort="Zottig, Ximena" uniqKey="Zottig X" first="Ximena" last="Zottig">Ximena Zottig</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Canada/explor/ParkinsonCanadaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000C81 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000C81 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Canada
|area= ParkinsonCanadaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:3889681
|texte= Resveratrol Protects DAergic PC12 Cells from High Glucose-Induced Oxidative Stress and Apoptosis: Effect on p53 and GRP75 Localization
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:24218232" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a ParkinsonCanadaV1
| This area was generated with Dilib version V0.6.29. |  |